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Cellosaurus BT172 (CVCL_IP12)

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Cell line name BT172
Synonyms BT-172; BT 172; CPDM_1284X
Accession CVCL_IP12
Resource Identification Initiative To cite this cell line use: BT172 (RRID:CVCL_IP12)
Comments Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Characteristics: Low-passage-number culture.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=25184684; DOI=10.1371/journal.pone.0106694; PMCID=PMC4153667
Karl Holmberg Olausson, Cecile L. Maire, Samer Haidar, Jason Ling, Emily Learner, Monica Nister, Keith Lloyd Ligon;
Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.
PLoS ONE 9:e106694.1-e106694.11(2014)

PubMed=25366336; DOI=10.1093/neuonc/nou303; PMCID=PMC4482855
Adam L. Green, Shakti H. Ramkissoon, Dilara McCauley, Kristen Jones, Jennifer A. Perry, Jessie Hao-Ru Hsu, Lori A. Ramkissoon, Cecile L. Maire, Benjamin Hubbell-Engler, David S. Knoff, Sharon Shacham ...Show all 13 authors... , Keith Lloyd Ligon, Andrew Li-Jen Kung; Show fewer authors
Preclinical antitumor efficacy of selective exportin 1 inhibitors in glioblastoma.
Neuro-oncol. 17:697-707(2015)

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Max A. Stockslager, Seth Malinowski, Mehdi Touat, Jennifer C. Yoon, Jack Geduldig, Mahnoor Mirza, Annette Sunhi Kim, Patrick Yung-Chih Wen, Kin-Hoe Chow, Keith Lloyd Ligon, Scott R. Manalis;
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Cross-references
Anatomy/cell type resources BTO; BTO_0005953
Chemistry resources PharmacoDB; BT172_121_2019
Encyclopedic resources Wikidata; Q54798424
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number8