ID   BT172
AC   CVCL_IP12
SY   BT-172; BT 172; CPDM_1284X
DR   BTO; BTO_0005953
DR   PharmacoDB; BT172_121_2019
DR   Wikidata; Q54798424
RX   PubMed=25184684;
RX   PubMed=25366336;
RX   PubMed=34610309;
CC   Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
CC   Characteristics: Low-passage-number culture.
CC   Characteristics: Can grow as a neurosphere (PubMed=34610309).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 10-04-25; Version: 8
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RX   PubMed=25184684; DOI=10.1371/journal.pone.0106694; PMCID=PMC4153667;
RA   Holmberg Olausson K., Maire C.L., Haidar S., Ling J., Learner E.,
RA   Nister M., Ligon K.L.;
RT   "Prominin-1 (CD133) defines both stem and non-stem cell populations in
RT   CNS development and gliomas.";
RL   PLoS ONE 9:e106694.1-e106694.11(2014).
//
RX   PubMed=25366336; DOI=10.1093/neuonc/nou303; PMCID=PMC4482855;
RA   Green A.L., Ramkissoon S.H., McCauley D., Jones K., Perry J.A.,
RA   Hsu J.H.-R., Ramkissoon L.A., Maire C.L., Hubbell-Engler B., Knoff D.S.,
RA   Shacham S., Ligon K.L., Kung A.L.-J.;
RT   "Preclinical antitumor efficacy of selective exportin 1 inhibitors in
RT   glioblastoma.";
RL   Neuro-oncol. 17:697-707(2015).
//
RX   PubMed=34610309; DOI=10.1016/j.celrep.2021.109788;
RA   Stockslager M.A., Malinowski S., Touat M., Yoon J.C., Geduldig J.,
RA   Mirza M., Kim A.S., Wen P.Y.-C., Chow K.-H., Ligon K.L., Manalis S.R.;
RT   "Functional drug susceptibility testing using single-cell mass
RT   predicts treatment outcome in patient-derived cancer neurosphere
RT   models.";
RL   Cell Rep. 37:109788.1-109788.12(2021).
//