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Cellosaurus KB-CP.5 (CVCL_IP04)

[Text version]
Cell line name KB-CP.5
Synonyms KCP.5
Accession CVCL_IP04
Resource Identification Initiative To cite this cell line use: KB-CP.5 (RRID:CVCL_IP04)
Comments Problematic cell line: Contaminated. Grand-parent cell line (KB) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2088 (KB-3-1)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=22571463; DOI=10.1021/mp300153z; PMCID=PMC3367311
Ding-Wu Shen, Lynn M. Pouliot, Jean-Pierre Gillet, Wen-Ting Ma, Alfred C. Johnson, Matthew D. Hall, Michael Marc Gottesman;
The transcription factor GCF2 is an upstream repressor of the small GTPAse RhoA, regulating membrane protein trafficking, sensitivity to doxorubicin, and resistance to cisplatin.
Mol. Pharm. 9:1822-1833(2012)

Cross-references
Anatomy/cell type resources BTO; BTO_0005849
Encyclopedic resources Wikidata; Q54899555
Gene expression databases GEO; GSM743497
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number11