ID   KB-CP.5
AC   CVCL_IP04
SY   KCP.5
DR   BTO; BTO_0005849
DR   GEO; GSM743497
DR   Wikidata; Q54899555
RX   PubMed=22571463;
CC   Problematic cell line: Contaminated. Grand-parent cell line (KB) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2088 ! KB-3-1
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 10-04-25; Version: 11
//
RX   PubMed=22571463; DOI=10.1021/mp300153z; PMCID=PMC3367311;
RA   Shen, Ding-Wu
RA   Pouliot, Lynn M.
RA   Gillet, Jean-Pierre
RA   Ma, Wen-Ting
RA   Johnson, Alfred C.
RA   Hall, Matthew D.
RA   Gottesman, Michael Marc
RT   "The transcription factor GCF2 is an upstream repressor of the small
RT   GTPAse RhoA, regulating membrane protein trafficking, sensitivity to
RT   doxorubicin, and resistance to cisplatin.";
RL   Mol. Pharm. 9:1822-1833(2012).
//