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Cellosaurus Tesi (CVCL_IN51)

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Cell line name Tesi
Accession CVCL_IN51
Resource Identification Initiative To cite this cell line use: Tesi (RRID:CVCL_IN51)
Comments Characteristics: Immortalized using a tetracycline-repressible HTLV-1 Tax gene.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1) (Note=Tax).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Cell type: T-cell; CL=CL_0000084.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling <1D
Category Transformed cell line
Publications

PubMed=9420268; DOI=10.1128/JVI.72.1.633-640.1998; PMCID=PMC109417
Iris Schmitt, Oliver Rosin, Peter Rohwer, Manfred Gossen, Ralph Grassmann;
Stimulation of cyclin-dependent kinase activity and G1- to S-phase transition in human lymphocytes by the human T-cell leukemia/lymphotropic virus type 1 Tax protein.
J. Virol. 72:633-640(1998)

PubMed=18276843; DOI=10.1182/blood-2007-10-115220
Klemens Pichler, Tarek Kattan, Juliane Gentzsch, Andrea K. Kress, Graham P. Taylor, Charles R.M. Bangham, Ralph Grassmann;
Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1-infected cultured and patients' T cells by the viral Tax oncoprotein.
Blood 111:4741-4751(2008)

Cross-references
Encyclopedic resources Wikidata; Q54972192
Gene expression databases GEO; GSE10508
Entry history
Entry creation01-Dec-2016
Last entry update10-Apr-2025
Version number11