ID   Tesi
AC   CVCL_IN51
DR   GEO; GSE10508
DR   Wikidata; Q54972192
RX   PubMed=9420268;
RX   PubMed=18276843;
CC   Characteristics: Immortalized using a tetracycline-repressible HTLV-1 Tax gene.
CC   Characteristics: IL2 dependent.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1) (Note=Tax).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
CC   Cell type: T-cell; CL=CL_0000084.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   <1D
CA   Transformed cell line
DT   Created: 01-12-16; Last updated: 10-04-25; Version: 11
//
RX   PubMed=9420268; DOI=10.1128/JVI.72.1.633-640.1998; PMCID=PMC109417;
RA   Schmitt I., Rosin O., Rohwer P., Gossen M., Grassmann R.;
RT   "Stimulation of cyclin-dependent kinase activity and G1- to S-phase
RT   transition in human lymphocytes by the human T-cell
RT   leukemia/lymphotropic virus type 1 Tax protein.";
RL   J. Virol. 72:633-640(1998).
//
RX   PubMed=18276843; DOI=10.1182/blood-2007-10-115220;
RA   Pichler K., Kattan T., Gentzsch J., Kress A.K., Taylor G.P.,
RA   Bangham C.R.M., Grassmann R.;
RT   "Strong induction of 4-1BB, a growth and survival promoting
RT   costimulatory receptor, in HTLV-1-infected cultured and patients' T
RT   cells by the viral Tax oncoprotein.";
RL   Blood 111:4741-4751(2008).
//