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Cellosaurus PT-r (CVCL_HF63)

[Text version]

Cell line name PT-r
Accession CVCL_HF63
Resource Identification Initiative To cite this cell line use: PT-r (RRID:CVCL_HF63)
Comments Doubling time: ~20 hours (PubMed=3472208).
Derived from sampling site: Parathyroid gland.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley.
Hierarchy Children:
CVCL_HF64 (PT-r 1)CVCL_HF65 (PT-r 2)CVCL_HF66 (PT-r 3)
CVCL_HF67 (PT-r 4)CVCL_HF62 (PTH-C1)
Sex of cell Male
Age at sampling 3M
Category Spontaneously immortalized cell line

PubMed=3472208; DOI=10.1073/pnas.84.10.3269
Sakaguchi K., Santora A., Zimering M., Curcio F., Aurbach G.D., Brandi M.L.
Functional epithelial cell line cloned from rat parathyroid glands.
Proc. Natl. Acad. Sci. U.S.A. 84:3269-3273(1987)

PubMed=2768284; DOI=10.1016/S0021-9258(19)84891-3
Yanagishita M., Brandi M.L., Sakaguchi K.
Characterization of proteoglycans synthesized by a rat parathyroid cell line.
J. Biol. Chem. 264:15714-15720(1989)

PubMed=1700579; DOI=10.1002/jbmr.5650050810
Sakaguchi K., Ikeda K., Curcio F., Aurbach G.D., Brandi M.L.
Subclones of a rat parathyroid cell line (PT-r): regulation of growth and production of parathyroid hormone-related peptide (PTHRP).
J. Bone Miner. Res. 5:863-869(1990)

PubMed=20558332; DOI=10.1016/j.bone.2010.05.031
Kawahara M., Iwasaki Y., Sakaguchi K., Taguchi T., Nishiyama M., Nigawara T., Kambayashi M., Sawada T., Jing X., Miyajima M., Terada Y., Hashimoto K., Suda T.
Involvement of GCMB in the transcriptional regulation of the human parathyroid hormone gene in a parathyroid-derived cell line PT-r: effects of calcium and 1,25(OH)2D3.
Bone 47:534-541(2010)

PubMed=24627164; DOI=10.1007/s12020-014-0229-7
Fabbri S., Ciuffi S., Nardone V., Gomes A.R., Mavilia C., Zonefrati R., Galli G., Luzi E., Tanini A., Brandi M.L.
PTH-C1: a rat continuous cell line expressing the parathyroid phenotype.
Endocrine 47:90-99(2014)

Cell line collections RCB; RCB4548
Encyclopedic resources Wikidata; Q54948626
Entry history
Entry creation01-Dec-2016
Last entry update20-May-2021
Version number4