ID   PT-r
AC   CVCL_HF63
DR   RCB; RCB4548
DR   Wikidata; Q54948626
RX   PubMed=1700579;
RX   PubMed=2768284;
RX   PubMed=3472208;
RX   PubMed=20558332;
RX   PubMed=24627164;
CC   Doubling time: ~20 hours (PubMed=3472208).
CC   Derived from site: In situ; Parathyroid gland; UBERON=UBERON_0001132.
CC   Breed/subspecies: Sprague Dawley; RS=RS_0000681.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
AG   3M
CA   Spontaneously immortalized cell line
DT   Created: 01-12-16; Last updated: 10-04-25; Version: 8
//
RX   PubMed=1700579; DOI=10.1002/jbmr.5650050810;
RA   Sakaguchi K., Ikeda K., Curcio F., Aurbach G.D., Brandi M.L.;
RT   "Subclones of a rat parathyroid cell line (PT-r): regulation of growth
RT   and production of parathyroid hormone-related peptide (PTHRP).";
RL   J. Bone Miner. Res. 5:863-869(1990).
//
RX   PubMed=2768284; DOI=10.1016/S0021-9258(19)84891-3;
RA   Yanagishita M., Brandi M.L., Sakaguchi K.;
RT   "Characterization of proteoglycans synthesized by a rat parathyroid
RT   cell line.";
RL   J. Biol. Chem. 264:15714-15720(1989).
//
RX   PubMed=3472208; DOI=10.1073/pnas.84.10.3269; PMCID=PMC304850;
RA   Sakaguchi K., Santora A., Zimering M., Curcio F., Aurbach G.D.,
RA   Brandi M.L.;
RT   "Functional epithelial cell line cloned from rat parathyroid glands.";
RL   Proc. Natl. Acad. Sci. U.S.A. 84:3269-3273(1987).
//
RX   PubMed=20558332; DOI=10.1016/j.bone.2010.05.031;
RA   Kawahara M., Iwasaki Y., Sakaguchi K., Taguchi T., Nishiyama M.,
RA   Nigawara T., Kambayashi M., Sawada T., Jing X.-F., Miyajima M.,
RA   Terada Y., Hashimoto K., Suda T.;
RT   "Involvement of GCMB in the transcriptional regulation of the human
RT   parathyroid hormone gene in a parathyroid-derived cell line PT-r:
RT   effects of calcium and 1,25(OH)2D3.";
RL   Bone 47:534-541(2010).
//
RX   PubMed=24627164; DOI=10.1007/s12020-014-0229-7;
RA   Fabbri S., Ciuffi S., Nardone V., Gomes A.R., Mavilia C.,
RA   Zonefrati R., Galli G., Luzi E., Tanini A., Brandi M.L.;
RT   "PTH-C1: a rat continuous cell line expressing the parathyroid
RT   phenotype.";
RL   Endocrine 47:90-99(2014).
//