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Cellosaurus MIP/CPT (CVCL_HE63)

[Text version]
Cell line name MIP/CPT
Accession CVCL_HE63
Resource Identification Initiative To cite this cell line use: MIP/CPT (RRID:CVCL_HE63)
Comments Selected for resistance to: ChEBI; CHEBI_80630; Irinotecan (Camptothecin-11; CPT-11).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Unspecified (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H689 (MIP-101)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=15902309; DOI=10.1172/JCI23002; PMCID=PMC1090471
Tai I.T., Dai M., Owen D.A., Chen L.-B.
Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy.
J. Clin. Invest. 115:1492-1502(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HE63
Encyclopedic resources Wikidata; Q54905754
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number9