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Cellosaurus MIP/5FU (CVCL_HE61)

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Cell line name MIP/5FU
Synonyms MIP/5-FU; MIP5FU
Accession CVCL_HE61
Resource Identification Initiative To cite this cell line use: MIP/5FU (RRID:CVCL_HE61)
Comments Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Unspecified (from parent cell line).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*24:02,02:01
HLA-BB*35:08,35:08
HLA-CC*07:01,04:01
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H689 (MIP-101)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=15902309; DOI=10.1172/JCI23002; PMCID=PMC1090471
Isabella T. Tai, Meiru Dai, David A. Owen, Lan-Bo Chen;
Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy.
J. Clin. Invest. 115:1492-1502(2005)

PubMed=20835245; DOI=10.1038/nmeth.1503
Malachi Griffith, Obi L. Griffith, Jill Mwenifumbo, Rodrigo Goya, Anca Sorana Morrissy, Ryan D. Morin, Richard D. Corbett, Michelle J. Tang, Ying-Chen Hou, Trevor J. Pugh, Gordon Robertson ...Show all 26 authors... , Suganthi Chittaranjan, Adrian Ally, Jennifer K. Asano, Susanna Y. Chan, Hai-Yan I. Li, Helen McDonald, Kevin Teague, Yong-Jun Zhao, Thomas Zeng, Allen Delaney, Martin Hirst, Gregg B. Morin, Steven J.M. Jones, Isabella T. Tai, Marco Antonio Marra; Show fewer authors
Alternative expression analysis by RNA sequencing.
Nat. Methods 7:843-847(2010)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Sebastian Boegel, Martin Lower, Thomas Bukur, Ugur Sahin, John C. Castle;
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HE61
Encyclopedic resources Wikidata; Q54905752
Gene expression databases GEO; GSM587039
Entry history
Entry creation01-Dec-2016
Last entry update10-Apr-2025
Version number12