Cellosaurus cell line (CVCL

Cellosaurus (CVCL_HE52)

Comments

Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Phenotyping; shRNA library screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Caution: Was incorrectly indicated to have an EWSR1-FLI1 (EWS-FLI1) gene fusion in PubMed=23637631.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=19787792).
Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=26428435; PubMed=33460449).
Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=19787792).

HLA typing

Source: PubMed=26589293

Class I
HLA-A	A*11:01,24:02
HLA-B	B*15:01,40:01
HLA-C	C*04:01,07:02

Genome ancestry

Source: PubMed=30894373

Origin	% genome
African	1.63
Native American	0.72
East Asian, North	75.38
East Asian, South	21.78
South Asian	0
European, North	0
European, South	0.48

Disease

Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)

Species of origin

Mus musculus (Mouse) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

19Y