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Cellosaurus INT-MEL-16/2 (CVCL_HE37)

[Text version]
Cell line name INT-MEL-16/2
Synonyms Me9923/M; Me9923
Accession CVCL_HE37
Resource Identification Initiative To cite this cell line use: INT-MEL-16/2 (RRID:CVCL_HE37)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:914; B2M; Simple; p.Asp79fs*6 (c.235_248del14); Zygosity=Homozygous (PubMed=9637706).
  • Mutation; HGNC; HGNC:914; B2M; Simple; p.Tyr86Ter (c.258C>G); Zygosity=Homozygous (PubMed=9637706).
HLA typing Source: PubMed=9637706
Class I
HLA-AA*02
HLA-BB*41,50
HLA-CC*w02,06
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_F250 ! INT-MEL-16/1
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
Publications

PubMed=9637706; DOI=10.1172/JCI498; PMCID=PMC508863
Daniel J. Hicklin, Zhi-Gang Wang, Flavio Arienti, Licia Rivoltini, Giorgio Parmiani, Soldano Ferrone;
Beta2-microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.
J. Clin. Invest. 101:2720-2729(1998)

DOI=10.1007/0-306-46872-7_16
Andrea Anichini, Roberta Mortarini, Claudia Vegetti, Alessandra Molla, Alessandra Borri, Giorgio Parmiani;
Melanoma: the Milan melanoma cell lines.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.283-292; Kluwer Academic Publishers; New York; USA (1999)

Cross-references
Encyclopedic resources Wikidata; Q54897762
Polymorphism and mutation databases Cosmic; 2759874
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number10