| Cell line name |
INT-MEL-16/1 |
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| Synonyms |
Me9923/P; Me9923p; Me9923; Me 9923; 9923 |
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| Accession |
CVCL_F250 |
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| Resource Identification Initiative |
To cite this cell line use: INT-MEL-16/1 (RRID:CVCL_F250) |
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| Sequence variations |
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Asp79fs*6 (c.235_248del14); Zygosity=Homozygous (PubMed=9637706).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Tyr86Ter (c.258C>G); Zygosity=Homozygous (PubMed=9637706).
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| HLA typing |
Source: PubMed=9637706
| Class I | | HLA-A | A*02 | | HLA-B | B*41,50 | | HLA-C | C*w02,06 |
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Originate from same individual |
CVCL_HE37 ! INT-MEL-16/2 |
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| Sex of cell |
Female |
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| Age at sampling |
65Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=9637706; DOI=10.1172/JCI498; PMCID=PMC508863
Daniel J. Hicklin, Zhi-Gang Wang, Flavio Arienti, Licia Rivoltini, Giorgio Parmiani, Soldano Ferrone;
Beta2-microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.
J. Clin. Invest. 101:2720-2729(1998) DOI=10.1007/0-306-46872-7_16
Andrea Anichini, Roberta Mortarini, Claudia Vegetti, Alessandra Molla, Alessandra Borri, Giorgio Parmiani;
Melanoma: the Milan melanoma cell lines.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.283-292; Kluwer Academic Publishers; New York; USA (1999) DOI=10.13130/grazia-giulia_phd2016-02-18
Giulia Grazia;
Co-targeting of oncogenic and death receptors pathways in human melanoma: pre-clinical rationale for a pro-apoptotic and anti-angiogenic strategy.
Thesis PhD (2015); Universita degli studi di Milano; Milano; Italy |
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| Cross-references |
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| Cell line databases/resources |
CLO; CLO_0001015
CLDB; cl141
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| Encyclopedic resources |
Wikidata; Q54897761
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| Polymorphism and mutation databases |
Cosmic; 720622
Cosmic; 2759875
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 14 |
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