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Cellosaurus CH-157MN-LucNeo (CVCL_HA68)

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Cell line name CH-157MN-LucNeo
Synonyms CH-157-MN-LucNeo
Accession CVCL_HA68
Resource Identification Initiative To cite this cell line use: CH-157MN-LucNeo (RRID:CVCL_HA68)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Brain, meninges; UBERON=UBERON_0010743.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Meningioma (NCIt: C3230)
Meningioma (ORDO: Orphanet_2495)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5723 (CH-157MN)
Sex of cell Female
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=18240927; DOI=10.3171/jns/2008/108/2/0304
Brian Thomas Ragel, Isaac L. Elam, David L. Gillespie, Jeannette R. Flynn, David A. Kelly, David Mabey, Harvey Feng, William Tupper Couldwell, Randy Lynn Jensen;
A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells.
J. Neurosurg. 108:304-310(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HA68
Encyclopedic resources Wikidata; Q54811595
Entry history
Entry creation01-Dec-2016
Last entry update14-Aug-2025
Version number12