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Cellosaurus J774.16 (CVCL_HA24)

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Cell line name J774.16
Synonyms J774 clone 16; J774 1.6; J774-1.6
Accession CVCL_HA24
Resource Identification Initiative To cite this cell line use: J774.16 (RRID:CVCL_HA24)
Comments Characteristics: Has a marked increase in the ability to reduce nitroblue tetrazolium (NBT) after stimulation with PMA (PubMed=6252274).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse reticulum cell sarcoma (NCIt: C134780)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_4692 (J774)
Children:
CVCL_C1MG (J774.C3C)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=6252274; DOI=10.1084/jem.152.4.808; PMCID=PMC2185959
Guido Damiani, Chiharu Kiyotaki, Walter Soeller, Masataka Sasada, Jack Peisach, Barry R. Bloom;
Macrophage variants in oxygen metabolism.
J. Exp. Med. 152:808-822(1980)

PubMed=7045866; DOI=10.1073/pnas.79.8.2584; PMCID=PMC346244
Yoshinori Tanaka, Chiharu Kiyotaki, Herbert Tanowitz, Barry R. Bloom;
Reconstitution of a variant macrophage cell line defective in oxygen metabolism with a H2O2-generating system.
Proc. Natl. Acad. Sci. U.S.A. 79:2584-2588(1982)

PubMed=6350185; DOI=10.1128/IAI.41.3.1322-1331.1983; PMCID=PMC264642
Yoshinori Tanaka, Herbert Tanowitz, Barry R. Bloom;
Growth of Trypanosoma cruzi in a cloned macrophage cell line and in a variant defective in oxygen metabolism.
Infect. Immun. 41:1322-1331(1983)

PubMed=3792703; DOI=10.1111/j.1432-0436.1986.tb00568.x
Pieter J.M. Leenen, Anita M.A.C. Jansen, Willem van Ewijk;
Murine macrophage cell lines can be ordered in a linear differentiation sequence.
Differentiation 32:157-164(1986)

Cross-references
Cell line collections (Providers) BCRJ; 0273
Encyclopedic resources Wikidata; Q54898486
Entry history
Entry creation26-Sep-2016
Last entry update05-Oct-2023
Version number7