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Cellosaurus AG01522 (CVCL_H759)

[Text version]
Cell line name AG01522
Synonyms AG-1522; AG 1522; AG1522; AG01522B; AGO 1522; AGO1522; AG1522D; 1522
Accession CVCL_H759
Resource Identification Initiative To cite this cell line use: AG01522 (RRID:CVCL_H759)
Comments Group: Space-flown cell line (cellonaut).
Anecdotal: Have been flown in space on the ISS to study growth in microgravity (PubMed=28248986).
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3D
Category Finite cell line
STR profile Source(s): NCBI_Iran=C449

Markers:
AmelogeninX
CSF1PO10
D5S81810
D7S82015
D8S117912,14
D13S3179,10
D16S53910
D18S5112
D21S1129,30
FGA20,25
TH019
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; -; -; http://faculty.washington.edu/trawets/archive/Human/fibroblast/ag1522/index.html
Publications

DOI=10.5962/bhl.title.4090
Lewis Lemon Coriell, Arthur E. Greene;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977)

CLPUB00387
Lewis Lemon Coriell, Arthur E. Greene, Richard A. Mulivor;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 7th edition. October 1980.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda; USA (1980)

PubMed=7374661; DOI=10.1016/0027-5107(80)90164-5
John Bertram Little, John Nove, Ralph R. Weichselbaum;
Abnormal sensitivity of diploid skin fibroblasts from a family with Gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C.
Mutat. Res. 70:241-250(1980)

PubMed=7471105
Ralph R. Weichselbaum, John Nove, John Bertram Little;
X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders.
Cancer Res. 40:920-925(1980)

PubMed=7253718; DOI=10.1016/0047-6374(81)90027-0
Nirmal K. Das, Donald G. Murphy;
The National Institute on Aging repository cell cultures.
Mech. Ageing Dev. 16:1-17(1981)

PubMed=7329430; DOI=10.1016/0027-5107(81)90059-2
John Nove, Warren W. Nichols, Ralph R. Weichselbaum, John Bertram Little;
Abnormalities of human chromosome 13 and in vitro radiosensitivity; a study of 19 fibroblast strains.
Mutat. Res. 84:157-167(1981)

PubMed=6810166; DOI=10.1016/0027-5107(82)90299-8
Thomas R. Barfknecht, John Bertram Little;
Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents.
Mutat. Res. 94:369-382(1982)

PubMed=7104995
Timothy James Kinsella, James B. Mitchell, Scott McPherson, Angelo Russo, Frank Tietze;
In vitro X-ray sensitivity in ataxia telangiectasis homozygote and heterozygote skin fibroblasts under oxic and hypoxic conditions.
Cancer Res. 42:3950-3956(1982)

PubMed=6843573; DOI=10.1016/0027-5107(83)90054-4
Hatsumi Nagasawa, John Bertram Little;
Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts.
Mutat. Res. 109:297-308(1983)

PubMed=6148444; DOI=10.1093/jnci/73.4.801
George Morstyn, Angelo Russo, Desmond Niall Carney, Essam Karawya, Samuel H. Wilson Jr., James B. Mitchell;
Heterogeneity in the radiation survival curves and biochemical properties of human lung cancer cell lines.
J. Natl. Cancer Inst. 73:801-807(1984)

PubMed=6442144; DOI=10.1007/978-1-4684-4892-4_20
Hatsumi Nagasawa, Frederic Fletcher Little, Maureen J. Burke, Ellen F. McCone, Harris S. Targovnik, Gerald L. Chan, John Bertram Little;
Study of basal cell nevus syndrome fibroblasts after treatment with DNA-damaging agents.
Basic Life Sci. 29:775-785(1984)

PubMed=2897722; DOI=10.1002/tcm.1770080104
Hatsumi Nagasawa, Maureen J. Burke, Frederic Fletcher Little, Ellen F. McCone, Gerald L. Chan, John Bertram Little;
Multiple abnormalities in the ultraviolet light response of cultured fibroblasts derived from patients with the basal cell nevus syndrome.
Teratog. Carcinog. Mutagen. 8:25-33(1988)

PubMed=2973075; DOI=10.2307/3577479
Bernard Fertil, Patrick J. Deschavanne, Danielle Debieu, Edmond-Philippe Malaise;
Correlation between PLD repair capacity and the survival curve of human fibroblasts in exponential growth phase: analysis in terms of several parameters.
Radiat. Res. 116:74-88(1988)

PubMed=3182330; DOI=10.1016/0360-3016(88)90125-3
Jeffrey L. Schwartz, Jacob Rotmensch, Susan Giovanazzi, Marvin B. Cohen, Ralph R. Weichselbaum;
Faster repair of DNA double-strand breaks in radioresistant human tumor cells.
Int. J. Radiat. Oncol. Biol. Phys. 15:907-912(1988)

PubMed=2559742; DOI=10.1002/mc.2940020606
Yoshio Kano, John Bertram Little;
Efficient immortalization by SV40 T DNA of skin fibroblasts from patients with Wilms' tumor associated with chromosome 11p deletion.
Mol. Carcinog. 2:314-321(1989)

PubMed=2380097; DOI=10.1016/0360-3016(90)90136-8
Dennis E. Hallahan, Michael A. Beckett, Donald William Kufe, Ralph R. Weichselbaum;
The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
Int. J. Radiat. Oncol. Biol. Phys. 19:69-74(1990)

PubMed=1845955
Brian L. Samuels, Judith L. Murray, Marvin B. Cohen, Ahmad R. Safa, Birandra K. Sinha, Alan J. Townsend, Michael A. Beckett, Ralph R. Weichselbaum;
Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance.
Cancer Res. 51:521-527(1991)

PubMed=1574572; DOI=10.2307/3578273
Edward J. Dunphy, Michael A. Beckett, Lawrence H. Thompson, Ralph R. Weichselbaum;
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Radiat. Res. 130:166-170(1992)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=19896956; DOI=10.1016/j.mrfmmm.2009.10.013
Paul F. Wilson, Peter B. Nham, Salustra S. Urbin, John M. Hinz, Irene M. Jones, Lawrence H. Thompson;
Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation.
Mutat. Res. 683:91-97(2010)

PubMed=21149446; DOI=10.1074/jbc.M110.204065; PMCID=PMC3059052
Sergei V. Kozlov, Mark E. Graham, Burkhard Jakob, Frank Tobias, Amanda W. Kijas, Marcel Tanuji, Philip Chen, Phillip James Robinson, Gisela Taucher-Scholz, Keiji Suzuki, Sairai So ...Show all 13 authors... , David Chen, Martin Francis Lavin; Show fewer authors
Autophosphorylation and ATM activation: additional sites add to the complexity.
J. Biol. Chem. 286:9107-9119(2011)

PubMed=28248986; DOI=10.1371/journal.pone.0170358; PMCID=PMC5332164
Tao Lu, Ye Zhang, Yared Kidane, Alan Harold Feiveson, Louis S. Stodieck, Fathi Karouia, Govindarajan Ramesh, Larry Rohde, Hong-Lu Wu;
Cellular responses and gene expression profile changes due to bleomycin-induced DNA damage in human fibroblasts in space.
PLoS ONE 12:e0170358.1-e0170358.19(2017)

Cross-references
Cell line collections (Providers) Coriell; AG01522
NCBI_Iran; C449
Cell line databases/resources CLO; CLO_0036902
Encyclopedic resources Wikidata; Q54609458
Gene expression databases GEO; GSE93860
GEO; GSM520723
GEO; GSM520724
GEO; GSM520725
GEO; GSM520726
GEO; GSM520727
GEO; GSM520728
GEO; GSM520729
GEO; GSM520730
GEO; GSM520731
GEO; GSM520732
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number24