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Cellosaurus AG01522 (CVCL_H759)

[Text version]
Cell line name AG01522
Synonyms AG-1522; AG 1522; AG1522; AG01522B; AGO 1522; AGO1522; AG1522D; 1522
Accession CVCL_H759
Resource Identification Initiative To cite this cell line use: AG01522 (RRID:CVCL_H759)
Comments Group: Space-flown cell line (cellonaut).
Anecdotal: Have been flown in space on the ISS to study growth in microgravity (PubMed=28248986).
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3D
Category Finite cell line
STR profile Source(s): NCBI_Iran


Run an STR similarity search on this cell line
Web pages http://faculty.washington.edu/trawets/archive/Human/fibroblast/ag1522/index.html

Coriell L.L., Greene A.E.
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977)

Coriell L.L., Greene A.E., Mulivor R.A.
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 7th edition. October 1980.
(In) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda (1980)

PubMed=7374661; DOI=10.1016/0027-5107(80)90164-5
Little J.B., Nove J., Weichselbaum R.R.
Abnormal sensitivity of diploid skin fibroblasts from a family with Gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C.
Mutat. Res. 70:241-250(1980)

Weichselbaum R.R., Nove J., Little J.B.
X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders.
Cancer Res. 40:920-925(1980)

PubMed=7253718; DOI=10.1016/0047-6374(81)90027-0
Das N.K., Murphy D.G.
The National Institute on Aging repository cell cultures.
Mech. Ageing Dev. 16:1-17(1981)

PubMed=7329430; DOI=10.1016/0027-5107(81)90059-2
Nove J., Nichols W.W., Weichselbaum R.R., Little J.B.
Abnormalities of human chromosome 13 and in vitro radiosensitivity; a study of 19 fibroblast strains.
Mutat. Res. 84:157-167(1981)

PubMed=6810166; DOI=10.1016/0027-5107(82)90299-8
Barfknecht T.R., Little J.B.
Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents.
Mutat. Res. 94:369-382(1982)

Kinsella T.J., Mitchell J.B., McPherson S., Russo A., Tietze F.
In vitro X-ray sensitivity in ataxia telangiectasis homozygote and heterozygote skin fibroblasts under oxic and hypoxic conditions.
Cancer Res. 42:3950-3956(1982)

PubMed=6843573; DOI=10.1016/0027-5107(83)90054-4
Nagasawa H., Little J.B.
Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts.
Mutat. Res. 109:297-308(1983)

PubMed=6148444; DOI=10.1093/jnci/73.4.801
Morstyn G., Russo A., Carney D.N., Karawya E., Wilson S.H., Mitchell J.B.
Heterogeneity in the radiation survival curves and biochemical properties of human lung cancer cell lines.
J. Natl. Cancer Inst. 73:801-807(1984)

PubMed=6442144; DOI=10.1007/978-1-4684-4892-4_20
Nagasawa H., Little F.F., Burke M.J., McCone E.F., Targovnik H.S., Chan G.L., Little J.B.
Study of basal cell nevus syndrome fibroblasts after treatment with DNA-damaging agents.
Basic Life Sci. 29:775-785(1984)

PubMed=2897722; DOI=10.1002/tcm.1770080104
Nagasawa H., Burke M.J., Little F.F., McCone E.F., Chan G.L., Little J.B.
Multiple abnormalities in the ultraviolet light response of cultured fibroblasts derived from patients with the basal cell nevus syndrome.
Teratog. Carcinog. Mutagen. 8:25-33(1988)

PubMed=2973075; DOI=10.2307/3577479
Fertil B., Deschavanne P.J., Debieu D., Malaise E.-P.
Correlation between PLD repair capacity and the survival curve of human fibroblasts in exponential growth phase: analysis in terms of several parameters.
Radiat. Res. 116:74-88(1988)

PubMed=3182330; DOI=10.1016/0360-3016(88)90125-3
Schwartz J.L., Rotmensch J., Giovanazzi S., Cohen M.B., Weichselbaum R.R.
Faster repair of DNA double-strand breaks in radioresistant human tumor cells.
Int. J. Radiat. Oncol. Biol. Phys. 15:907-912(1988)

PubMed=2559742; DOI=10.1002/mc.2940020606
Kano Y., Little J.B.
Efficient immortalization by SV40 T DNA of skin fibroblasts from patients with Wilms' tumor associated with chromosome 11p deletion.
Mol. Carcinog. 2:314-321(1989)

PubMed=2380097; DOI=10.1016/0360-3016(90)90136-8
Hallahan D.E., Beckett M.A., Kufe D.W., Weichselbaum R.R.
The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
Int. J. Radiat. Oncol. Biol. Phys. 19:69-74(1990)

Samuels B.L., Murray J.L., Cohen M.B., Safa A.R., Sinha B.K., Townsend A.J., Beckett M.A., Weichselbaum R.R.
Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance.
Cancer Res. 51:521-527(1991)

PubMed=1574572; DOI=10.2307/3578273
Dunphy E.J., Beckett M.A., Thompson L.H., Weichselbaum R.R.
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Radiat. Res. 130:166-170(1992)

National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994)

PubMed=19896956; DOI=10.1016/j.mrfmmm.2009.10.013
Wilson P.F., Nham P.B., Urbin S.S., Hinz J.M., Jones I.M., Thompson L.H.
Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation.
Mutat. Res. 683:91-97(2010)

PubMed=21149446; DOI=10.1074/jbc.M110.204065
Kozlov S.V., Graham M.E., Jakob B., Tobias F., Kijas A.W., Tanuji M., Chen P., Robinson P.J., Taucher-Scholz G., Suzuki K., So S., Chen D., Lavin M.F.
Autophosphorylation and ATM activation: additional sites add to the complexity.
J. Biol. Chem. 286:9107-9119(2011)

PubMed=28248986; DOI=10.1371/journal.pone.0170358
Lu T., Zhang Y., Kidane Y., Feiveson A., Stodieck L., Karouia F., Ramesh G., Rohde L., Wu H.-L.
Cellular responses and gene expression profile changes due to bleomycin-induced DNA damage in human fibroblasts in space.
PLoS ONE 12:E0170358-E0170358(2017)

Cell line collections (Providers) Coriell; AG01522
NCBI_Iran; C449
Cell line databases/resources CLO; CLO_0036902
Encyclopedic resources Wikidata; Q54609458
Gene expression databases GEO; GSE93860
GEO; GSM520723
GEO; GSM520724
GEO; GSM520725
GEO; GSM520726
GEO; GSM520727
GEO; GSM520728
GEO; GSM520729
GEO; GSM520730
GEO; GSM520731
GEO; GSM520732
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number22