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Cellosaurus A2780-cisR (CVCL_H745)

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Cell line name A2780-cisR
Synonyms A2780-CISR; A2780/cisR; A2780cisR; A2780(cisR)
Accession CVCL_H745
Resource Identification Initiative To cite this cell line use: A2780-cisR (RRID:CVCL_H745)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Omics: Metabolomics.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu365Lys (c.1093G>A); ClinVar=VCV000419222; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:17271; RRAS2; Simple; p.Gln72Leu (c.215A>T); ClinVar=VCV000009447; Zygosity=Homozygous (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_H745
Chemistry resources ChEMBL-Cells; CHEMBL3307508
ChEMBL-Targets; CHEMBL614023
PubChem_Cell_line; CVCL_H745
Encyclopedic resources Wikidata; Q54606563
Metabolomic databases MetaboLights; MTBLS156
MetaboLights; MTBLS1014
Polymorphism and mutation databases Cosmic; 688091
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number23