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Cellosaurus 3134 (CVCL_H641)

[Text version]
Cell line name 3134
Accession CVCL_H641
Resource Identification Initiative To cite this cell line use: 3134 (RRID:CVCL_H641)
Comments Group: Patented cell line.
Part of: ENCODE project mouse cell lines.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11998.
Characteristics: Contains 200 copies of the pM18 plasmid. pM18 contains a MMTV LTR promoter (the LTR contains GR-binding sites) driven ha-v-ras and a 69% transforming fragment of bovine papilloma virus type 1 (BPV1) (from parent cell line).
Characteristics: Has undergone a spontaneous integration and amplification of the pM18 episome in the genome (PubMed=10497225).
Genetic integration: Method=Transfection; Gene=UniProtKB; P01115; Harvey murine sarcoma virus H-Ras (V-Ha-ras).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: RIII.
Hierarchy Parent: CVCL_Z933 (904.13)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; ENCODE; -; http://genome.ucsc.edu/ENCODE/protocols/cell/mouse/3134_Stam_protocol.pdf
Publications

PubMed=10497225; DOI=10.1074/jbc.274.40.28590
Phillip R. Kramer, Gilberto Fragoso, William Pennie, Han Htun, Gordon L. Hager, Richard R. Sinden;
Transcriptional state of the mouse mammary tumor virus promoter can affect topological domain size in vivo.
J. Biol. Chem. 274:28590-28597(1999)

Patent=US7312032
Han Htun, Gordon L. Hager;
Methods for screening ligands that activate the translocation of a steroid receptor to the nucleus in mammalian cells.
Patent number US7312032, 25-Dec-2007

Cross-references
Biological sample resources ENCODE; ENCBS023ENC
ENCODE; ENCBS655OXH
Encyclopedic resources Wikidata; Q54584727
Experimental variables resources EFO; EFO_0007069
Gene expression databases GEO; GSM1014196
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number15