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Cellosaurus GM1500-6TG-A11 (CVCL_H615)

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Cell line name GM1500-6TG-A11
Synonyms GM1500 6TG-A11; GM 1500 6TG-A11; GM 1500 6TG A11; GM1500 6TG A-11; GM 1500 6TG-A1 1; 6TG-A11; GM04672; GM 4672; GM4672; GM04672B
Accession CVCL_H615
Secondary accession CVCL_F607
Resource Identification Initiative To cite this cell line use: GM1500-6TG-A11 (RRID:CVCL_H615)
Comments Group: Hybridoma fusion partner cell line.
Group: Patented cell line.
Problematic cell line: Misclassified. Parent cell line (GM01500) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8032.
Population: Caucasian.
Characteristics: Secretes IgG2 kappa (Coriell=GM04672).
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Misspelling: GM1500-GTG-A11; Note=Occasionally.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D870 (GM01500)
Children:
CVCL_D5ZK (BEG-2)CVCL_H617 (GM1500-6TG-OUB)CVCL_2526 (HuNS1)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=6969366; DOI=10.1038/288488a0
Carlo Maria Croce, Alban Linnenbach, William W. Hall, Zenon Steplewski, Hilary Koprowski;
Production of human hybridomas secreting antibodies to measles virus.
Nature 288:488-489(1980)

PubMed=7085884; DOI=10.1172/JCI110595; PMCID=PMC370244
Yehuda Shoenfeld, Shu-Chun Hsu-Lin, Joseph E. Gabriels, Leslie Eric Silberstein, Barbara C. Furie, Bruce E. Furie, Bernard David Stollar, Robert S. Schwartz;
Production of autoantibodies by human-human hybridomas.
J. Clin. Invest. 70:205-208(1982)

PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201
Paul G. Abrams, James A. Knost, Gregory Clarke, Shannon Wilburn, Robert K. Oldham, Kenneth Alan Foon;
Determination of the optimal human cell lines for development of human hybridomas.
J. Immunol. 131:1201-1204(1983)

PubMed=6864164; DOI=10.1084/jem.158.1.53; PMCID=PMC2187084
Alan N. Houghton, Hannah Brooks, Richard J. Cote, Michael C. Taormina, Herbert Friedrich Oettgen, Lloyd John Old;
Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.
J. Exp. Med. 158:53-65(1983)

Patent=US4608337
Carlo Maria Croce;
Human hybridomas and the production of human monoclonal antibodies by human hybridomas.
Patent number US4608337, 26-Aug-1986

CLPUB00447
Richard A. Mulivor, Sharon F. Suchy;
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=7689347; DOI=10.3233/HAB-1993-4303
John D. Rioux, Joyce Rauch, Emanuel Zdarsky, Marianna M. Newkirk;
Molecular characterization of the GM 4672 human lymphoblastoid cell line and analysis of its use as a fusion partner in the generation of human-human hybridoma autoantibodies.
Hum. Antibodies Hybridomas 4:107-114(1993)

PubMed=8357959; DOI=10.3233/HAB-1993-4301
Gregory A. Denomme, Mahmoud Mahmoudi, Jane Y. Edwards, Helene Massicotte, Ewa Cairns, David A. Bell;
Immunoglobulin V region heavy and light chain gene sequences of the lymphoblastoid cell line GM 4672.
Hum. Antibodies Hybridomas 4:98-103(1993)

Cross-references
Cell line collections (Providers) Coriell; GM04672
Cell line databases/resources CLO; CLO_0019017
Encyclopedic resources Wikidata; Q54847545
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number20