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Cellosaurus BE-NQ7 (CVCL_H585)

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Cell line name BE-NQ7
Synonyms BE-NQ
Accession CVCL_H585
Resource Identification Initiative To cite this cell line use: BE-NQ7 (RRID:CVCL_H585)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2874; NQO1.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (from parent cell line).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H580 (BE [Human colon carcinoma])
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=9865924
Shannon Lee Winski, Robert H.J. Hargreaves, John Butler, David Ross;
A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
Clin. Cancer Res. 4:3083-3088(1998)

PubMed=11377380; DOI=10.1016/S0006-2952(01)00631-1
Shannon Lee Winski, Elizabeth Swann, Robert H.J. Hargreaves, Donna L. Dehn, John Butler, Christopher J. Moody, David Ross;
Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones.
Biochem. Pharmacol. 61:1509-1516(2001)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307688
ChEMBL-Targets; CHEMBL614702
PubChem_Cell_line; CVCL_H585
Encyclopedic resources Wikidata; Q54795861
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number13