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Cellosaurus GHR3 (CVCL_H544)

[Text version]
Cell line name GHR3
Synonyms GM15923
Accession CVCL_H544
Resource Identification Initiative To cite this cell line use: GHR3 (RRID:CVCL_H544)
Comments Problematic cell line: Contaminated. Ancestral cell line (Ej138) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Characteristics: Derived from spontaneous HPRT- mutant of EJ30.
Transfected with: UniProtKB; P0A9M5; Escherichia coli gpt.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F666 (EJ-30tgr)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=9419347; DOI=10.1073/pnas.95.1.167
Clarke D.J., Gimenez-Abian J.F., Tonnies H., Neitzel H., Sperling K., Downes C.S., Johnson R.T.
Creation of monosomic derivatives of human cultured cell lines.
Proc. Natl. Acad. Sci. U.S.A. 95:167-171(1998)

Cross-references
Cell line collections (Providers) Coriell; GM15923
Cell line databases/resources CLO; CLO_0018740
cancercelllines; CVCL_H544
Encyclopedic resources Wikidata; Q54835800
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number15