ID   GHR3
AC   CVCL_H544
SY   GM15923
DR   CLO; CLO_0018740
DR   cancercelllines; CVCL_H544
DR   Coriell; GM15923
DR   Wikidata; Q54835800
RX   PubMed=9419347;
CC   Problematic cell line: Contaminated. Ancestral cell line (Ej138) has been shown to be a T24 derivative.
CC   Population: Caucasian; Swedish.
CC   Characteristics: Derived from spontaneous HPRT- mutant of EJ30.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P0A9M5; Escherichia coli gpt.
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_F666 ! EJ-30tgr
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 15
//
RX   PubMed=9419347; DOI=10.1073/pnas.95.1.167;
RA   Clarke D.J., Gimenez-Abian J.F., Tonnies H., Neitzel H., Sperling K.,
RA   Downes C.S., Johnson R.T.;
RT   "Creation of monosomic derivatives of human cultured cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:167-171(1998).
//