Cellosaurus cell line 1321N1/P2Y1 (CVCL

Cross-references
Cell line name	1321N1/P2Y1
Accession	CVCL_H355
Resource Identification Initiative	To cite this cell line use: 1321N1/P2Y1 (RRID:CVCL_H355)
Comments	Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative. Population: Caucasian. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:8539; P2RY1. Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
Disease	Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0110 (1321N1)
Sex of cell	Male
Age at sampling	47Y
Category	Cancer cell line
Cell line collections (Providers)	GenScript; M00250
Cell line databases/resources	cancercelllines; CVCL_H355
Encyclopedic resources	Wikidata; Q54581489
Entry history
Entry creation	11-Feb-2013
Last entry update	10-Apr-2025
Version number	21