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Cellosaurus St-4 (CVCL_H265)

[Text version]
Cell line name St-4
Accession CVCL_H265
Resource Identification Initiative To cite this cell line use: St-4 (RRID:CVCL_H265)
Comments Part of: JFCR39 cancer cell line panel.
Part of: JFCR45 cancer cell line panel.
Population: Japanese.
Omics: Transcriptomics; Microarray.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr205del (c.613_615delTAT); Zygosity=Unspecified (PubMed=15900046).
Disease Gastric carcinoma (NCIt: C4911)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_Y176 (St-4/cDDP)CVCL_H266 (St-4/CPT)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2170010
Yoshikazu Sugimoto, Satomi Tsukahara, Tomoko Oh-hara, Toshiyuki Isoe, Takashi Tsuruo;
Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody.
Cancer Res. 50:6925-6930(1990)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Noriyuki Nakatsu, Yoko Yoshida, Kanami Yamazaki, Tomoki Nakamura, Shingo Dan, Yasuhisa Fukui, Takao Yamori;
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

PubMed=15900046; DOI=10.1093/jnci/dji133
Tetsuo Mashima, Tomoko Oh-hara, Shigeo Sato, Mikiko Mochizuki, Yoshikazu Sugimoto, Kanami Yamazaki, Jun-ichi Hamada, Mitsuhiro Tada, Tetsuya Moriuchi, Yuichi Ishikawa, Yo Kato ...Show all 14 authors... , Hiroshi Tomoda, Takao Yamori, Takashi Tsuruo; Show fewer authors
p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.
J. Natl. Cancer Inst. 97:765-777(2005)

PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017
De-Xin Kong, Takao Yamori;
JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.
Bioorg. Med. Chem. 20:1947-1951(2012)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307553
ChEMBL-Targets; CHEMBL614166
PubChem_Cell_line; CVCL_H265
Encyclopedic resources Wikidata; Q54955732
Polymorphism and mutation databases Cosmic; 1436022
IARC_TP53; 21647
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number18