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Cellosaurus U-87MG Uppsala (CVCL_GP63)

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Cell line name U-87MG Uppsala
Synonyms U-87MG; U-87 MG; U87 MG; U-87-MG; U87-MG; U87MG; U-87; U87; 87 MG; 87MG
Accession CVCL_GP63
Resource Identification Initiative To cite this cell line use: U-87MG Uppsala (RRID:CVCL_GP63)
Comments Caution: This is the original U-87MG cell line established in 1968 at the University of Uppsala. The cell line distributed by most cell collections (including ATCC, CLS, ECACC, etc.) is a different cell line whose origin is not yet clear (PubMed=27582061). See U-87MG ATCC (Cellosaurus=CVCL_0022) for the cell line used by most research groups.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): PubMed=27582061

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,20
D3S135815
D5S81811,12
D7S82010,13
D8S117913,14
D13S31711,12
D16S5399,13
D19S43314,15
D21S1128,30
FGA20,24
Penta D11
Penta E7,13
TH018,9
TPOX8,11
vWA15,19

Run an STR similarity search on this cell line
Web pages Info; Wikipedia; -; https://en.wikipedia.org/wiki/U87
Publications

PubMed=4313504; DOI=10.1111/j.1699-0463.1968.tb03502.x
Jan Ponten, Elisabeth H. Macintyre;
Long term culture of normal and neoplastic human glia.
Acta Pathol. Microbiol. Scand. 74:465-486(1968)

PubMed=4337530; DOI=10.1111/j.1699-0463.1972.tb02176.x
Elisabeth H. Macintyre, Jan Ponten, Albert E. Vatter;
The ultrastructure of human and murine astrocytes and of human fibroblasts in culture.
Acta Pathol. Microbiol. Scand. A. 80:267-283(1972)

PubMed=4134536; DOI=10.1002/ijc.2910120215
Bengt Westermark;
The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture.
Int. J. Cancer 12:438-451(1973)

PubMed=4369403; DOI=10.1002/1097-0142(197408)34:2<274::AID-CNCR2820340209>3.0.CO;2-4
Torsten Wahlstrom, Ewert Linder, Eero Saksela, Bengt Westermark;
Tumor-specific membrane antigens in established cell lines from gliomas.
Cancer 34:274-279(1974)

DOI=10.1007/978-1-4757-1647-4_7
Jan Ponten;
Neoplastic human glia cells in culture.
(In book chapter) Human tumor cells in vitro; Fogh, Jorgen (eds.); pp.175-206; Springer; New York; USA (1975)

PubMed=2454731
Monica Nister, Towia Aron Libermann, Christer Betsholtz, Monica Pettersson, Lena Claesson-Welsh, Carl-Henrik Heldin, Joseph Schlessinger, Bengt Westermark;
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Cancer Res. 48:3910-3918(1988)

DOI=10.1016/B978-0-12-333530-2.50005-8
Monica Nister, Bengt Westermark;
Human glioma cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.17-42; Academic Press; New York; USA (1994)

DOI=10.1007/0-306-46861-1_11
Francis Ali-Osman;
Brain tumors.
(In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999)

PubMed=27582061; DOI=10.1126/scitranslmed.aaf6853
Marie Allen, Mia Bjerke, Hanna Edlund, Sven Nelander, Bengt Westermark;
Origin of the U87MG glioma cell line: good news and bad news.
Sci. Transl. Med. 8:354re3.1-354re3.4(2016)

Cross-references
Encyclopedic resources Wikidata; Q28575999
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number8