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Cellosaurus ME-F2/ADM100 (CVCL_G315)

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Cell line name ME-F2/ADM100
Accession CVCL_G315
Resource Identification Initiative To cite this cell line use: ME-F2/ADM100 (RRID:CVCL_G315)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:1539; CBFB + HGNC; HGNC:7569; MYH11; Name(s)=CBFB-MYH11 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000375871; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_G313 (ME-F2)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=9177449; DOI=10.1038/sj.leu.2400663
Yuji Utsunomiya, Hitoshi Hasegawa, Kohsuke Yanagisawa, Shigeru Fujita;
Enhancement of mdr1 gene expression by transforming growth factor-beta1 in the new adriamycin-resistant human leukemia cell line ME-F2/ADM.
Leukemia 11:894-895(1997)

Cross-references
Cell line databases/resources cancercelllines; CVCL_G315
Encyclopedic resources Wikidata; Q54904907
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number17