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Cellosaurus ME-F2 (CVCL_G313)

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Cell line name ME-F2
Synonyms Me-F2
Accession CVCL_G313
Resource Identification Initiative To cite this cell line use: ME-F2 (RRID:CVCL_G313)
Comments Population: Japanese.
Doubling time: 2-3 days (PubMed=8018932).
Omics: Proteomics; PTM; Phosphorylation; Quantitative.
Caution: It is possible that ME-F2 and ME-1f2 (Cellosaurus=CVCL_WS58) are the same cell line.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:1539; CBFB + HGNC; HGNC:7569; MYH11; Name(s)=CBFB-MYH11 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000375871; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_RL95 (ME-2)
Children:
CVCL_G315 (ME-F2/ADM100)CVCL_G316 (ME-F2/ADM200)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=8018932; DOI=10.1182/blood.V84.1.84.84
Kohsuke Yanagisawa, Masateru Sato, Takahiko Horiuchi, Hitoshi Hasegawa, Shigeru Fujita;
Difference in response to colony-stimulating factors and involvement of protein kinase C signal transduction system in three subclones from the ME-1 cell line and two sublines.
Blood 84:84-93(1994)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=21552520; DOI=10.1371/journal.pone.0019169; PMCID=PMC3084268
Ting-Lei Gu, Julie Nardone, Yi Wang, Marc Loriaux, Judit Villen, Sean A. Beausoleil, Meghan Tucker, Jon M. Kornhauser, Jian-Min Ren, Joan MacNeill, Steven P. Gygi ...Show all 15 authors... , Brian Jay Druker, Michael Charles Heinrich, John Rush, Roberto D. Polakiewicz; Show fewer authors
Survey of activated FLT3 signaling in leukemia.
PLoS ONE 6:e19169.1-e19169.10(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_G313
Encyclopedic resources Wikidata; Q54904906
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number20