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Cellosaurus A431/Luc GPC3- (CVCL_F6LF)

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Cell line name A431/Luc GPC3-
Synonyms AL1
Accession CVCL_F6LF
Resource Identification Initiative To cite this cell line use: A431/Luc GPC3- (RRID:CVCL_F6LF)
Comments Population: Caucasian.
Characteristics: Stably transduced with pLenti-C-Luciferase-P2A-Puro.
Characteristics: Control cell line for A431/Luc GPC3+ (Cellosaurus=CVCL_F6LE).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Miscellaneous: Cell line information from personal communication of Fayn, Stanley.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; HGNC:3236; EGFR + HGNC; HGNC:9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
Entry history
Entry creation22-Oct-2026
Last entry update22-Oct-2026
Version number1