Cellosaurus cell line A431/GPC3+ (CVCL

Cellosaurus A431/GPC3+ (CVCL_F6LD)

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Cell line name

A431/GPC3+

Synonyms

G1; A431-GPC3

Accession

CVCL_F6LD

Resource Identification Initiative

To cite this cell line use: A431/GPC3+ (RRID:CVCL_F6LD)

Comments

Population: Caucasian.
Characteristics: Stably expresses human GPC3.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4451; GPC3.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.

Sequence variations

Gene fusion; HGNC; HGNC:3236; EGFR + HGNC; HGNC:9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).

Disease

Skin squamous cell carcinoma (NCIt: C4819)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0037 (A-431)
Children:

CVCL_F6LE (A431/Luc GPC3+)

Sex of cell

Female

Age at sampling

85Y