Cellosaurus cell line EDITGENE HNRNPF (p.K224R, c.671A>G) Point Mutation in HT-29 Cell Line (CVCL

Cell line name

EDITGENE HNRNPF (p.K224R, c.671A>G) Point Mutation in HT-29 Cell Line

Synonyms

HNRNPF (p.K224R, c.671A>G) Point Mutation in HT-29 Cell Line

Accession

CVCL_F6EZ

To cite this cell line use: EDITGENE HNRNPF (p.K224R, c.671A>G) Point Mutation in HT-29 Cell Line (RRID:CVCL_F6EZ)

Comments

Population: Caucasian.
Characteristics: Growth mode Adherent.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.

Sequence variations

Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:5039; HNRNPF; Simple_edited; p.K224R (c.671A>G); Zygosity=Unspecified; Note=By CRISPR/Cas9 (EDITGENE=EDC90377).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0320 (HT-29)

Sex of cell

Female

Age at sampling

44Y