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Cellosaurus EDITGENE U-937-CopGFP (CVCL_F6BN)

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Cell line name EDITGENE U-937-CopGFP
Synonyms U-937-CopGFP
Accession CVCL_F6BN
Resource Identification Initiative To cite this cell line use: EDITGENE U-937-CopGFP (RRID:CVCL_F6BN)
Comments Population: Caucasian.
Characteristics: Growth mode Suspension.
Genetic integration: Method=Transduction; Gene=FPbase; 2BK6M; ppluGFP2 (copGFP, green fluorescent protein from P.plumata).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:16063; MLLT10 + HGNC; HGNC:15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC01374

Markers:
AmelogeninX
CSF1PO12
D2S44110
D2S133817,20
D3S135816
D5S81812
D7S8209,11
D8S117912,13
D12S39117,18
D13S31710,12
D16S53912
D18S5113,14
D19S43314,16
D21S1127,29
FGA22,24,25
Penta D12,13
Penta E13
TH016,9.3
TPOX8,11
vWA14,15

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Cross-references
Cell line collections (Providers) EDITGENE; EDC01374
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1