Cellosaurus cell line EDITGENE MAPK7 (p.D200A) Point Mutation in Ishikawa Cell Line (CVCL

Cell line name

EDITGENE MAPK7 (p.D200A) Point Mutation in Ishikawa Cell Line

Synonyms

MAPK7 (p.D200A) Point Mutation in Ishikawa Cell Line

Accession

CVCL_F5YI

To cite this cell line use: EDITGENE MAPK7 (p.D200A) Point Mutation in Ishikawa Cell Line (RRID:CVCL_F5YI)

Comments

Population: Japanese.
Characteristics: Growth mode Adherent.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.

Sequence variations

Mutation; HGNC; HGNC:6880; MAPK7; Simple_edited; p.D200A; Zygosity=Unspecified; Note=By CRISPR/Cas9 (EDITGENE=EDC07573).
Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Ser302fs*4 (c.906delC); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).

Disease

Type I endometrial adenocarcinoma (NCIt: C40145)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_2529 (Ishikawa)

Sex of cell

Female

Age at sampling

39Y