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Cellosaurus EDITGENE 143B-FLUC (CVCL_F5UJ)

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Cell line name EDITGENE 143B-FLUC
Synonyms 143B-FLUC
Accession CVCL_F5UJ
Resource Identification Initiative To cite this cell line use: EDITGENE 143B-FLUC (RRID:CVCL_F5UJ)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2270 (143B)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC01258

Markers:
CSF1PO12
D5S81813
D7S82011,12
D13S31712
D16S53910,13
TH016
TPOX11
vWA18

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Cross-references
Cell line collections (Providers) EDITGENE; EDC01258
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1