Cellosaurus logo
expasy logo

Cellosaurus EDITGENE 786-O-FLUC (CVCL_F5UC)

[Text][XML][JSON]
Cell line name EDITGENE 786-O-FLUC
Synonyms 786-O-FLUC
Accession CVCL_F5UC
Resource Identification Initiative To cite this cell line use: EDITGENE 786-O-FLUC (RRID:CVCL_F5UC)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln149Ter (c.445C>T); ClinVar=VCV000404164; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.560-2A>G; ClinVar=VCV003148158; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Ala (c.832C>G); ClinVar=VCV000376645; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Gly104Alafs*55 (c.311delG); Zygosity=Homozygous (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1051 (786-O)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC01276

Markers:
AmelogeninX,Y
CSF1PO10
D2S44110,11
D2S133817,18
D3S135816
D5S8189
D6S104311
D7S82011,12
D8S117913
D12S39117,18
D13S3178
D16S53912
D18S5113,14
D19S43314,15
D21S1129,30
FGA24
Penta D9,12
Penta E7,16
TH016,9.3
TPOX8,11
vWA15,17

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) EDITGENE; EDC01276
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1