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Cellosaurus EDITGENE RKO-FLUC (CVCL_F5TR)

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Cell line name EDITGENE RKO-FLUC
Synonyms RKO-FLUC
Accession CVCL_F5TR
Resource Identification Initiative To cite this cell line use: EDITGENE RKO-FLUC (RRID:CVCL_F5TR)
Comments Characteristics: Growth mode Adherent.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0504 (RKO)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC01414

Markers:
AmelogeninX
CSF1PO8,10
D2S133816
D3S135816,19
D5S81811,13
D6S104313.1,14.1,19,20
D7S8208,10
D8S11799,13,14
D12S39115,19,20,21
D13S3178,11
D16S53913
D18S5111,12
D19S43314
D21S1127,29,30
FGA20,21,22,23
Penta D10,11
Penta E11,13
TH016,10
TPOX11
vWA16,17,21,22

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Cross-references
Cell line collections (Providers) EDITGENE; EDC01414
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1