ID   EDITGENE RKO-FLUC
AC   CVCL_F5TR
SY   RKO-FLUC
DR   EDITGENE; EDC01414
CC   Characteristics: Growth mode Adherent.
CC   Sequence variation: Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): EDITGENE=EDC01414
ST   Amelogenin: X
ST   CSF1PO: 8,10
ST   D12S391: 15,19,20,21
ST   D13S317: 8,11
ST   D16S539: 13
ST   D18S51: 11,12
ST   D19S433: 14
ST   D21S11: 27,29,30
ST   D2S1338: 16
ST   D3S1358: 16,19
ST   D5S818: 11,13
ST   D6S1043: 13.1,14.1,19,20
ST   D7S820: 8,10
ST   D8S1179: 9,13,14
ST   FGA: 20,21,22,23
ST   Penta D: 10,11
ST   Penta E: 11,13
ST   TH01: 6,10
ST   TPOX: 11
ST   vWA: 16,17,21,22
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0504 ! RKO
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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