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Cellosaurus EDITGENE F2R Knockout SK-N-SH Cell Line (CVCL_F5FH)

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Cell line name EDITGENE F2R Knockout SK-N-SH Cell Line
Synonyms F2R Knockout SK-N-SH Cell Line
Accession CVCL_F5FH
Resource Identification Initiative To cite this cell line use: EDITGENE F2R Knockout SK-N-SH Cell Line (RRID:CVCL_F5FH)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:3537; F2R.
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0531 (SK-N-SH)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC07923

Markers:
AmelogeninX
CSF1PO11
D2S44111,11.3
D2S133817,19
D3S135815,16
D5S81812
D6S104312,18
D7S8207,10
D8S117915
D12S39118,22
D13S31711
D16S5398,13
D18S5113,16
D19S43313,14
D21S1131,31.2
FGA23.2,24
Penta D10,12
Penta E7,11
TH017,10
TPOX8,11
vWA14,18

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Cross-references
Cell line collections (Providers) EDITGENE; EDC07923
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1