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Cellosaurus EDITGENE APOE Knockout HEPG2 Cell Line (CVCL_F5CA)

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Cell line name EDITGENE APOE Knockout HEPG2 Cell Line
Synonyms APOE Knockout HEPG2 Cell Line
Accession CVCL_F5CA
Resource Identification Initiative To cite this cell line use: EDITGENE APOE Knockout HEPG2 Cell Line (RRID:CVCL_F5CA)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:613; APOE.
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC07735

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S44111.3,14
D2S133819,20
D3S135815,16
D5S81811,12
D6S104313
D7S82010
D8S117915,16
D12S39121,25
D13S3179,13
D16S53912
D18S5113,14
D19S43315.2
D21S1129,31
FGA22,25
Penta D9,13
Penta E15,20
TH019
TPOX8,9
vWA17

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Cross-references
Cell line collections (Providers) EDITGENE; EDC07735
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1