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Cellosaurus EDITGENE GPER1 Knockout AsPC-1 Cell Line (CVCL_F5BZ)

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Cell line name EDITGENE GPER1 Knockout AsPC-1 Cell Line
Synonyms GPER1 Knockout AsPC-1 Cell Line
Accession CVCL_F5BZ
Resource Identification Initiative To cite this cell line use: EDITGENE GPER1 Knockout AsPC-1 Cell Line (RRID:CVCL_F5BZ)
Comments Population: Caucasian.
Characteristics: Growth mode Adherent.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4485; GPER1.
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; HGNC:6844; MAP2K4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Leu78Hisfs*41 (c.233_234delTC) (p.His93Profs*67, c.276_277delTC); ClinVar=VCV000977782; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Arg100Thr (c.299G>C); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Alafs*35 (c.403delT); ClinVar=VCV001069265; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0152 (AsPC-1)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC07694

Markers:
AmelogeninX
CSF1PO10,13
D2S44111,14
D2S133822,23
D3S135816
D5S81812
D6S104311,20
D7S82012,13
D8S117913,15
D12S39119
D13S3179,12
D16S53911
D18S5118
D19S43314
D21S1128,30
FGA24
Penta D9,12
Penta E5,12
TH017,9.3
TPOX8,10
vWA17

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Cross-references
Cell line collections (Providers) EDITGENE; EDC07694
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1