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Cellosaurus HyCyte A2780 stable cell line for hSNCA overexpression (CVCL_F4WH)

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Cell line name HyCyte A2780 stable cell line for hSNCA overexpression
Synonyms A2780 stable cell line for hSNCA overexpression
Accession CVCL_F4WH
Resource Identification Initiative To cite this cell line use: HyCyte A2780 stable cell line for hSNCA overexpression (RRID:CVCL_F4WH)
Comments Population: African American.
Characteristics: Transfected with pPB[Exp]-EF1A>EGFP-CAG>hSNCA[NM_000345.4]*3xflag-PGK>Puro.
Doubling time: 18-24 hours (Hysigen=CGSC-M36261).
Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:11138; SNCA.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu365Lys (c.1093G>A); ClinVar=VCV000419222; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:17271; RRAS2; Simple; p.Gln72Leu (c.215A>T); ClinVar=VCV000009447; Zygosity=Homozygous (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M36261
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1