Cellosaurus cell line HyCyte TPC-1 stable cell line for hRPSAP52 overexpression (CVCL

Cellosaurus HyCyte TPC-1 stable cell line for hRPSAP52 overexpression (CVCL_F4WF)

Cross-references
Cell line name	HyCyte TPC-1 stable cell line for hRPSAP52 overexpression
Synonyms	TPC-1 stable cell line for hRPSAP52 overexpression
Accession	CVCL_F4WF
Resource Identification Initiative	To cite this cell line use: HyCyte TPC-1 stable cell line for hRPSAP52 overexpression (RRID:CVCL_F4WF)
Comments	Population: Japanese. Characteristics: Transfected with pPB[Exp]-EF1A>EGFP-CAG>hRPSAP52[NR_026825.2]-PGK>Puro. Doubling time: 18-24 hours (Hysigen=CGSC-M36201). Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP. Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:35752; RPSAP52. Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations	Gene fusion; HGNC; HGNC:18782; CCDC6 + HGNC; HGNC:9967; RET; Name(s)=CCDC6-RET, RET/PTC1 (from parent cell line). Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Ala68fs (c.204_208delGGAGC); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11355; STAG2; Simple; p.Gln1089Ter (c.3265C>T); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from parent cell line).
Disease	Thyroid gland papillary carcinoma (NCIt: C4035) Differentiated thyroid carcinoma (ORDO: Orphanet_146)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_6298 (TPC-1)
Sex of cell	Female
Age at sampling	Adult
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGSC-M36201
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1