Cellosaurus logo
expasy logo

Cellosaurus HyCyte HT-1080 stable cell line for hFAP overexpression (CVCL_F4TL)

[Text][XML][JSON]
Cell line name HyCyte HT-1080 stable cell line for hFAP overexpression
Synonyms HT-1080 stable cell line for hFAP overexpression
Accession CVCL_F4TL
Resource Identification Initiative To cite this cell line use: HyCyte HT-1080 stable cell line for hFAP overexpression (RRID:CVCL_F4TL)
Comments Population: Caucasian.
Characteristics: Transfected with pPB[Exp]-EF1A>EGFP-CAG>hFAP[NM_004460.5]-PGK>Puro.
Doubling time: 24-36 hours (Hysigen=CGSC-M34881).
Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:3590; FAP.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M34881
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1