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Cellosaurus HyCyte NALM-6 stable cell line for hP4HA2 overexpression (CVCL_F4RL)

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Cell line name HyCyte NALM-6 stable cell line for hP4HA2 overexpression
Synonyms NALM-6 stable cell line for hP4HA2 overexpression
Accession CVCL_F4RL
Resource Identification Initiative To cite this cell line use: HyCyte NALM-6 stable cell line for hP4HA2 overexpression (RRID:CVCL_F4RL)
Comments Population: Caucasian.
Characteristics: Transfected with pPB[Exp]-EF1A>luciferase-CAG>hP4HA2[NM_004199.3]*3×Flag-PGK>puro.
Doubling time: 24-36 hours (Hysigen=CGSC-M32731).
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:8547; P4HA2.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:50800; DUX4 + HGNC; HGNC:5477; IGH; Name(s)=IGH-DUX4; Note=The translocation occurs in the silenced IGH allele (from parent cell line).
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Ala146Thr (c.436G>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (from parent cell line).
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0092 (NALM-6)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M32731
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1