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Cellosaurus HyCyte NCI-H460 stable cell line for hFAP overexpression (CVCL_F4N7)

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Cell line name HyCyte NCI-H460 stable cell line for hFAP overexpression
Synonyms NCI-H460 stable cell line for hFAP overexpression
Accession CVCL_F4N7
Resource Identification Initiative To cite this cell line use: HyCyte NCI-H460 stable cell line for hFAP overexpression (RRID:CVCL_F4N7)
Comments Population: Caucasian.
Characteristics: Transfected with pPB[Exp]-EF1A>hFAP[NM_004460.5]-CMV>EGFP/Puro.
Doubling time: 36-48 hours (Hysigen=CGSC-M32841).
Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:3590; FAP.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0459 (NCI-H460)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M32841
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1