ID   HyCyte NCI-H460 stable cell line for hFAP overexpression
AC   CVCL_F4N7
SY   NCI-H460 stable cell line for hFAP overexpression
DR   Hysigen; CGSC-M32841
CC   Population: Caucasian.
CC   Characteristics: Transfected with pPB[Exp]-EF1A>hFAP[NM_004460.5]-CMV>EGFP/Puro.
CC   Doubling time: 36-48 hours (Hysigen=CGSC-M32841).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
CC   Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
CC   Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:3590; FAP.
CC   Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4450; Lung large cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0459 ! NCI-H460
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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