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Cellosaurus HyCyte HL-60 stable cell line for hHSPA5 overexpression (CVCL_F4LT)

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Cell line name HyCyte HL-60 stable cell line for hHSPA5 overexpression
Synonyms HL-60 stable cell line for hHSPA5 overexpression
Accession CVCL_F4LT
Resource Identification Initiative To cite this cell line use: HyCyte HL-60 stable cell line for hHSPA5 overexpression (RRID:CVCL_F4LT)
Comments Population: Caucasian.
Characteristics: Transfected with pPB[Exp]-EF1A-EGFP>CAG-hHSPA5[NM_005347.5]*3*flag>PGK-Puro.
Doubling time: 24-36 hours (Hysigen=CGSC-M27655).
Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:5238; HSPA5.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia with maturation (NCIt: C7961)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M27655
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1