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Cellosaurus HyCyte TPC-1 stable cell line for hLCN2 overexpression (CVCL_F4LL)

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Cell line name HyCyte TPC-1 stable cell line for hLCN2 overexpression
Synonyms TPC-1 stable cell line for hLCN2 overexpression
Accession CVCL_F4LL
Resource Identification Initiative To cite this cell line use: HyCyte TPC-1 stable cell line for hLCN2 overexpression (RRID:CVCL_F4LL)
Comments Population: Japanese.
Characteristics: Transfected with pPB[Exp]-EF1A-EGFP>CAG-hLCN2[NM_005564.5]>PGK-Puro.
Doubling time: 18-24 hours (Hysigen=CGSC-M27171).
Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:6526; LCN2.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Gene fusion; HGNC; HGNC:18782; CCDC6 + HGNC; HGNC:9967; RET; Name(s)=CCDC6-RET, RET/PTC1 (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Ala68fs (c.204_208delGGAGC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11355; STAG2; Simple; p.Gln1089Ter (c.3265C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from parent cell line).
Disease Thyroid gland papillary carcinoma (NCIt: C4035)
Differentiated thyroid carcinoma (ORDO: Orphanet_146)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6298 (TPC-1)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGSC-M27171
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1