Cellosaurus cell line HyCyte CT26 mKRAS_p.G12C_c.575G＞T cell line (CVCL

Cross-references
Cell line name	HyCyte CT26 mKRAS_p.G12C_c.575G＞T cell line
Synonyms	hKRAS_p.G12D_c.35G＞A cell line
Accession	CVCL_F4L3
Resource Identification Initiative	To cite this cell line use: HyCyte CT26 mKRAS_p.G12C_c.575G＞T cell line (RRID:CVCL_F4L3)
Comments	Population: Caucasian. Doubling time: 36-48 hours (Hysigen=CGMU-M2280). Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple_edited; p.G12D (NM_004985.5:c.35G>A); Zygosity=Homozygous (Hysigen=CGMU-M2280). Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0025 (Caco-2)
Sex of cell	Male
Age at sampling	72Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGMU-M2280
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1