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Cellosaurus HyCyte Hep-G2 hMAP3K7_p.T178R_c.533C>G cell line (CVCL_F4KG)

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Cell line name HyCyte Hep-G2 hMAP3K7_p.T178R_c.533C>G cell line
Synonyms hMAP3K7_p.T178R_c.533C>G cell line
Accession CVCL_F4KG
Resource Identification Initiative To cite this cell line use: HyCyte Hep-G2 hMAP3K7_p.T178R_c.533C>G cell line (RRID:CVCL_F4KG)
Comments Population: Caucasian.
Doubling time: 60-72 hours (Hysigen=CGMU-M2262).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:6859; MAP3K7; Simple_edited; p.T178R (NM_145331.3:c.533C>G); Zygosity=Homozygous (Hysigen=CGMU-M2262).
  • Mutation; HGNC; HGNC:6859; MAP3K7; Simple_edited; p.A179A (NM_145331.3:c.537C>A); Zygosity=Homozygous; Note=Synonymous mutation (Hysigen=CGMU-M2262).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGMU-M2262
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1