Cellosaurus cell line HyCyte TMD8 hBTK_p.L528W_c.1583T>G cell line (CVCL

Cross-references
Cell line name	HyCyte TMD8 hBTK_p.L528W_c.1583T>G cell line
Synonyms	hBTK_p.L528W_c.1583T>G cell line
Accession	CVCL_F4KA
Resource Identification Initiative	To cite this cell line use: HyCyte TMD8 hBTK_p.L528W_c.1583T>G cell line (RRID:CVCL_F4KA)
Comments	Population: Japanese. Doubling time: 36-48 hours (Hysigen=CGMU-M2176). Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:1133; BTK; Simple_edited; p.L528W (NM_000061.3:c.1583T>G); Zygosity=Homozygous (Hysigen=CGMU-M2176). Mutation; HGNC; HGNC:1699; CD79B; Simple; p.Tyr196His (c.586T>C); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Leu252Pro (c.755T>C) (p.Leu265Pro, c.794T>C) (L265P); ClinVar=VCV000037055; Zygosity=Heterozygous (from parent cell line).
Disease	Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081) Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_A442 (TMD8)
Sex of cell	Male
Age at sampling	62Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGMU-M2176
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1